Lyrica: an important medicine — dangerous when misused.
Prescribed for nerve pain and some other conditions — but high doses and mixing with other substances can lead to dependence and danger.
What is Lyrica?
Lyrica is a brand name for pregabalin, prescribed for nerve pain, some epilepsy and, in some countries, anxiety. It is sometimes misused at high doses for relaxation or a high, or to ease withdrawal from other substances.
Signs of misuse
- Doses above prescription, or none at all
- Drowsiness, dizziness, slurred speech
- Anxiety, insomnia and sweating when stopping
- Mixing it with tramadol or other painkillers
Risks
- Breathing suppression when mixed with opioids or alcohol — potentially fatal
- Dependence and withdrawal
- Accidents from drowsiness and dizziness
Withdrawal and treatment
Stopping suddenly after long use can cause insomnia, anxiety, nausea, sweating and, rarely, seizures. Tapering is therefore gradual and medically supervised, alongside treatment for what drove the use: pain, anxiety or another addiction.
How Restart helps
General educational content from the Restart team — not a substitute for a medical assessment. In an emergency, call emergency services immediately. · Last reviewed: November 2026
Medically reviewed byDr. Huthayfa BarhamMedical Director · Addiction psychiatristFAQ
Is Lyrica addictive?
How long does Lyrica stay in the body?
How dangerous is mixing Lyrica and tramadol?
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